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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNQ2
All Species:
8.48
Human Site:
S715
Identified Species:
26.67
UniProt:
O43526
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43526
NP_004509.2
872
95848
S715
P
P
V
Q
C
P
P
S
T
S
W
Q
P
Q
S
Chimpanzee
Pan troglodytes
XP_001149510
874
95647
S717
P
P
V
Q
C
P
P
S
T
S
W
Q
P
Q
S
Rhesus Macaque
Macaca mulatta
XP_001112016
932
102223
P752
P
T
T
L
Q
I
P
P
P
L
P
A
I
K
H
Dog
Lupus familis
XP_855335
921
101023
A764
K
N
F
S
A
P
P
A
G
P
P
A
Q
C
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z351
759
84432
D610
G
R
G
P
T
I
T
D
K
D
R
T
K
G
P
Rat
Rattus norvegicus
O88943
852
93931
S698
P
P
A
E
C
P
P
S
T
S
W
Q
Q
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506608
802
89095
Y653
T
S
W
Q
H
Q
A
Y
Q
R
Q
G
H
G
S
Chicken
Gallus gallus
Frog
Xenopus laevis
P70057
377
42627
E227
V
V
F
I
H
R
Q
E
L
I
T
T
L
Y
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
46.4
60.6
N.A.
69.3
92.8
N.A.
83.3
N.A.
22.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.3
59.8
66.7
N.A.
74
94.6
N.A.
86.9
N.A.
30.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
0
66.6
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
0
73.3
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
13
0
13
13
0
0
0
25
0
0
0
% A
% Cys:
0
0
0
0
38
0
0
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
0
0
0
0
0
13
0
13
0
0
0
0
0
% D
% Glu:
0
0
0
13
0
0
0
13
0
0
0
0
0
0
0
% E
% Phe:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
13
0
0
0
0
0
13
0
0
13
0
25
0
% G
% His:
0
0
0
0
25
0
0
0
0
0
0
0
13
0
25
% H
% Ile:
0
0
0
13
0
25
0
0
0
13
0
0
13
0
13
% I
% Lys:
13
0
0
0
0
0
0
0
13
0
0
0
13
13
0
% K
% Leu:
0
0
0
13
0
0
0
0
13
13
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
38
0
13
0
50
63
13
13
13
25
0
25
0
25
% P
% Gln:
0
0
0
38
13
13
13
0
13
0
13
38
25
25
0
% Q
% Arg:
0
13
0
0
0
13
0
0
0
13
13
0
0
0
0
% R
% Ser:
0
13
0
13
0
0
0
38
0
38
0
0
0
13
38
% S
% Thr:
13
13
13
0
13
0
13
0
38
0
13
25
0
0
0
% T
% Val:
13
13
25
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
13
0
0
0
0
0
0
0
38
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _